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Uncomplicated UTI’s in Adults

Bryan Hayes, PharmD, Mizuho Morrison, DO, and Mike Weinstock, MD
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22:28
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Acute uncomplicated cystitis is becoming more difficult to treat in the setting of increasing antimicrobial resistance. And treatment for uncomplicated cystitis seems to be constantly changing. Medication choices all have side effects that are concerning especially with renal/hepatic impairment. Bryan Hayes, Mike and Miz discuss current management of uncomplicated UTI’s.

 

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David S. -

Kind of curious if this fear of inducing cephalosporin resistance is warranted or not? I have heard competing inputs on whether using 3rd generation cephalosporins is appropriate for UTIs. UpToDate seems to point towards it being okay for certain bugs and a bad choice for others. Thoughts?

Mike W., MD -

I generally use macrobid or bactrim as a first line, but will occ use a 3rd gen oral cephalosporin if there is an allergy or resistance. As far as the resistance, it is not a common occurrence to use these meds and I agree w UTD that it is OK to use. Thx for the great comment!

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You Broke It Where?? Full episode audio for MD edition 198:23 min - 93 MB - M4Ahippo Urgent Care RAP - March 2017 Summary 328 KB - PDF