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*UPDATED* The Saga Continues with Remdesivir and Hydroxychloroquine

Salim Rezaie, MD

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*Editor's note: As of June 4, 2020, The Lancet article by Mehra MR et al has been retracted. (

In this Hippo Education short, Dr.Salim Rezaie from REBEL EM and Lit Matters critically appraises two papers published on Friday May 22nd, 2020.  He discusses what the evidence shows for both remdesivir & hydroxychloroquine/chloroquine as effective treatment or prophylaxis for COVID-19.

Released 6/10/20


  1. Beigel JH et al. Remdesivir for the Treatment of COVID-19 – Preliminary Report. NEJM 2020.

Jessica M., PA-C -

Have you heard of the MATH+ protocol? I'm interested in Hippo feedback on this for critical care management of COVID19.

Mike W., MD -

I am not aware that this protocol is helpful and that any of these items inc Vit C, thiamin, steroids etc has been shown to be effective against covid. This looks like a site which promotes natural/vitamin solutions to medical problems (on my very brief look at the site) so please be cautious w this!!

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