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Paper Chase #1: New CDC Treatment Guidelines for STIs

Nate Finnerty, MD and Brett Ebeling, MD
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The cdc guidelines for treatment of uncomplicated gonorrhea has changed from 250 mg to 500 mg of IM ceftriaxone. Azithromycin is no longer recommended for chlamydia; patients should receive doxycyline 100 mg bid for 7 days.

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Linda P. -

Per my reading of the CDC guidelines, a lab confirmed case of chlamydia may be treated with EITHER azithromycin 1 gram once or doxycycline 100 mg twice a day for 7 days. I think the recent research on GC shows that the organism is resistant to azithromycin, thus the change in guidelines to a large one time dose of ceftriaxone (it's the GC that is resistant to the azithro not the CT). The doxycycline is preferred when chlamydia has not been ruled out. If there is a lab confirmed case of GC, then only ceftriaxone is needed.

Mike W., MD -

Thx Linda!
Michael

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Hippo Urgent Care Written Summary April 2021 306 KB - PDF

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