Deadly Drug CombinationsFrom August 2021, T21, All Grown Up
We prescribe medications all the time in primary care. Sometimes, we prescribe something that can cause a lethal drug-drug interaction. Dr. Joe Martinez walks Neda through 4 common scenarios of well-intentioned drug-drug combos gone awry.19min 4Joe Martinez, MD and Neda Frayha, MD
Less is More, Some MoreFrom April 2021, Becoming Trauma Informed
Less is more! We were thrilled to learn about the JAMA Internal Medicine series highlighting which primary care services we can scale back on or do away with completely. In this month’s Primary Care RAP introduction, Neda and Paul continue breaking down some of these recommendations and how they’ll …15min 18Paul Simmons, MD and Neda Frayha, MD
GabapentinoidsFrom March 2021, Hidden Killers
It seems like gabapentin is prescribed for everything from hot flashes to dementia. Are we prescribing it appropriately? In this segment, Dr. Molly Heublein takes a deep dive into the use (and misuse) of gabapentinoids.17min 24Molly Heublein, MD and Neda Frayha, MD
Paper Chase #1: Antibiotics vs Appendectomy for AppendicitisFrom February 2021, Are You Keeping Up?
Antibiotics were not inferior to appendectomy at 90 days. 30% of the antibiotic group ended up having an appendectomy by 90 days.7min 26Steve Biederman, MD and Tom Robertson, MD
Paper Chase #3: Palliative Care and Chronic IllnessFrom February 2021, Are You Keeping Up?
Use of palliative care was associated with less acute healthcare use and modestly lower symptom burden, but there was no significant difference in quality of life.6min 28Steve Biederman, MD and Tom Robertson, MD
Paper Chase #4: Patient-Reported Errors in EHR NotesFrom February 2021, Are You Keeping Up?
Patients reported errors in medical documentation almost a quarter of the time, and half of those errors were deemed serious.6min 11Steve Biederman, MD and Tom Robertson, MD
All About AmitriptylineFrom February 2021, Are You Keeping Up?
What is the deal with amitriptyline? Is it a panacea? Or a pariah? PC RAP’s own Dr. Jay-Sheree Allen and Dr. Neda Frayha break it all down for us in this medication deep dive.16min 11Jay-Sheree Allen, MD and Neda Frayha, MD
Paper Chase #5: Smoking Cessation in New Cancer DiagnosesFrom February 2021, Are You Keeping Up?
Among smokers recently diagnosed with cancer, sustained counseling and provision of free cessation medication resulted in higher six month quit rates.6min 36Steve Biederman, MD and Tom Robertson, MD
Paper Chase #2: Memory Training for ChildrenFrom February 2021, Are You Keeping Up?
Computer games did not improve children's working memory at six months.5min 8Steve Biederman, MD and Tom Robertson, MD
Clonidine or Clonidon't?From September 2020, LARCs and SPIKES and Cryo, Oh My
What is the deal with clonidine? In this introduction to the September PC RAP episode, Neda and Paul answer some listener questions about this controversial medication.15min 9Paul Simmons, MD and Neda Frayha, MD
SGLT2 Inhibitors and GLP1 AgonistsFrom September 2020, LARCs and SPIKES and Cryo, Oh My
The world of diabetes management has changed dramatically in the past several years. Given the new ADA guidelines and all the new literature on SGLT2 inhibitors and GLP1 receptor antagonists, endocrinologist Dr. Beth Lamos is back to help us understand how to use these drugs in practice.26min 56Neda Frayha, MD and Elizabeth Lamos, MD
CBDFrom September 2020, LARCs and SPIKES and Cryo, Oh My
In recent years, CBD has become increasingly popular as a “cure” for ailments ranging from pain to anxiety. How much evidence is there to back up these claims? Drs. Michael Baca-Atlas and Hayden Shafer do a literature deep-dive.11min 28Hayden Schafer, MD and Michael Baca Atlas, MD
*UPDATED* The Saga Continues with Remdesivir and HydroxychloroquineFrom May 2020, *UPDATED* The Saga Continues with Remdesivir and Hydroxychloroquine
*Editor's note: As of June 4, 2020, The Lancet article by Mehra MR et al has been retracted. (https://www.thelancet.com/lancet/article/s0140673620313246) • In this Hippo Education short, Dr.Salim Rezaie from REBEL EM and Lit Matters critically appraises two papers published on Friday May 22nd …9min 19Salim Rezaie, MD
TIDBSI: TramadolFrom April 2020, More Listener Love
Tramadol - good or bad? This age-old question has been burning for decades. Today, Paul Simmons and Justin McCarthy will attempt to settle the matter once and for all in our latest Things I Do But Should I conversation. •16min 45Justin McCarthy, MD and Paul Simmons, MD
COVID-19 PharmacologyFrom April 2020, COVID-19 Pharmacology
Mizuho sits down with emergency medicine pharmacist/toxicologist Bryan Hayes, PharmD to answer some pertinent questions and myth-bust clarifications about pharmaceutical options in COIVD-19 treatment.17min 44Mizuho Morrison, DO and Bryan Hayes, PharmD
Meds in PregnancyFrom November 2019, Just Say No To Teratogens
Which meds are safe for a pregnant woman to take when she has a migraine? Upper respiratory tract infection? Back pain? Our listener Cassie asked, and Paul and Neda answer in the introduction to this month’s Primary Care RAP. •12min 55Neda Frayha, MD and Paul Simmons, MD
Penicillin Allergy in Primary CareFrom September 2019, Are We Better in the Morning?
We see “ALL: PCN” all the time. But how often is it true? And why does it matter? Neda sits down with Dr. Torie Grant, a Med/Peds Allergist and Immunologist at Johns Hopkins, to learn all about the risks attached to a penicillin allergy label and some easy approaches to debunking this allergy in …8min 32Torie Grant, MD MHS and Neda Frayha, MD
Penicillin Allergy: Fake News?From September 2019, Are We Better in the Morning?
We see “ALL: PCN” all the time. But how often is it true? And why does it matter? Neda sits down with Dr. Torie Grant, a Med/Peds Allergist and Immunologist at Johns Hopkins, to learn all about the risks attached to a penicillin allergy label and some easy approaches to debunking this allergy in …25min 11Neda Frayha, MD and Torie Grant, MD MHS
Tobacco Cessation - Part 1From August 2019, Primary Care Gets Some Love
Neda and Michael discuss the spectrum of outpatient tobacco cessation treatment including FDA approved pharmacotherapy, innovative strategies, and alternative/complementary treatments. •20min 33Michael Baca-Atlas, MD and Neda Frayha, MD
HIV Care for the Primary Care ClinicianFrom August 2019, Primary Care Gets Some Love
Can HIV be managed in the primary care setting? With today’s advances in antiretroviral therapy, the answer is yes. Infectious Diseases physician Dr. Devang Patel sits down with Miz and Neda for a conversation about the latest developments in HIV treatment. •24min 39Devang Patel, MD, Neda Frayha, MD, and Mizuho Morrison, DO
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