Paper Chase #3 - Cognitive Function in a Randomized Trial of EvolocumabFrom November 2017, Lytes and Bites
This 19 month trial did not find any clinically significant changes in cognitive functioning in patients taking evolucomab compared to placebo. •5min 14Andrew Buelt, DO and Joe Weatherly, DO
Post-Traumatic Bone Crusher HeadachesFrom October 2017, It's Bloody Halloween!
Just about any injury to the head can result in post-traumatic headache. The phenotype varies depending in part on the mechanism of injury. Treatment should be tailored to the presenting symptoms or phenotype. Physical modalities, medications, and cognitive behavioural therapy may all be …16min 39Jordan Roberts, PA-C
My kid is Freakin’ Seizing!! Simple Febrile SeizuresFrom October 2017, It's Bloody Halloween!
Simple febrile seizures are common and they are terrifying for parents. In this chapter, Casey reviews the AAP’s 2011 guidelines, reviews appropriate evaluation, discusses follow up recommendations, and emphasizes the importance of parental education and reassurance.20min 39Casey Parker, MD
Case of the Month: CIDPFrom September 2017, You Can Do It!!
CIDP is a bit of a mysterious condition. While it is more common than ALS, it’s underrecognized. It’s an auto-immune mediated condition and has been referred to as chronic Guillain-Barre. Treatments include IVIG, steroids, plasmapheresis and cytotoxic medications. •19min 53Adrien Selim, MD and Heidi James, MD
Paper Chase 5 - A Zap on the Back for Chronic Low PainFrom September 2017, You Can Do It!!
Radiofrequency denervation combined with an exercise program is no better at improving chronic low back pain than exercise alone.6min 6Andrew Buelt, DO and Joe Weatherly, DO
Multiple SclerosisFrom June 2017, Legions of Lesions
Multiple Sclerosis is a common neurological condition with diverse presentations including focal neurological symptoms. Symptoms lasting 24-48 hours and occurring over 30 days apart could be indicative of MS. Evaluation includes MRI with gadolinium of the head and C-spine. On MRI, classic …25min 33Neda Frayha, MD and Bob Shin, MD
Non-Sports ConcussionFrom May 2017, My Gut Biome Told Me So
Jordan Roberts provides an overview of concussion management in the non-athletes. The guiding principal is to gradually increase the amount of activities patients do, being very mindful to take a step back if symptoms worsen. Return to work and regular life activities will take time and it is wise …20min 53Jordan Roberts, PA-C and Vanessa Cardy, MD
Paper Chase 5: Amitriptyline, Topiramate, and Placebo for Pediatric MigraineFrom April 2017, Antibiotics in the Lyme-Light
In this study, neither topiramate nor amitriptyline were superior to placebo at preventing pediatric migraine. •4min 42Andrew Buelt, DO and Joe Weatherly, DO
HyperhidrosisFrom February 2017, Sweat Puddled, Brains Muddled
Hyperhidrosis is a common condition characterized by excessive sweating, most often occurring in the axilla. Treatment options include high concentration aluminum antiperspirants, botox injection, water iontophoresis, laser and surgery. •17min 40Heidi James, MD and Joe Weatherly, DO
What Do I Do Next? 41 Year Old Woman with Headache and Visual ChangeFrom December 2016, Ear Pain is but a Memory
Discuss neurologic assessment and distinction between concerning focal findings for stroke/TIA vs atypical migraine. •16min 7Colin Kaide, MD and Mike Weinstock, MD
Exercise Induced HyponatremiaFrom December 2016, Ear Pain is but a Memory
When is hyponatremia not treated like the usual hyponatremia you see in Grandma from the nursing home? When it is in a patient running 50 miles and drinking a LOT of water, that is when! •26min 3John Anderson, MD and Rob Orman, MD
Depression in Dementia: Dx and TxFrom December 2016, Ear Pain is but a Memory
Rob and Dr. Shawn Hersevoort discuss a psychiatric approach to evaluating and managing depression in patients with dementia. •12min 45Rob Orman, MD and Shawn Hersevoort, MD, MPH
Depression in Dementia: Advanced TxFrom December 2016, Ear Pain is but a Memory
Part two of Shawn Hersevoort's Guide to Managing Dementia in Depression. In this segment we focus on: use of stimulants, medications directed at slowing dementia, and managing depression associated with Parkinson's Disease. •19min 5Rob Orman, MD and Shawn Hersevoort, MD, MPH
Things I Do But Should I: Sacral DimplesFrom September 2016, Best Weight, Best Exercise!
Review an approach to the neonate with a sacral dimple.6min 44Vanessa Cardy, MD and Adrien Selim, MD
Paper Chase 1: Pimavanserin - A New Treatment for Parkinson’s Disease PsychosisFrom August 2016, Feeling Restless
Patients with Parkinson’s Disease psychosis treated with pimavanserin had decreased psychosis scores compared to those given placebo. •4min 57Andrew Buelt, DO and Joe Weatherly, DO
Introduction: Restless Leg SyndromeFrom August 2016, Feeling Restless
What's your favorite restless legs pharmacotherapy? Iron, dopamine agonists? Rob and Andrew go head to head and see what works and what doesn't. •13min 51Rob Orman, MD and Andrew Buelt, DO
Paper Chase 5: Treatment of Painful Diabetic NeuropathyFrom July 2016, Creme de la Thyroid
Several medications may be effective for short-term management of painful diabetic neuropathy, although their comparative effectiveness is unclear. •5min 5Andrew Buelt, DO and Joe Weatherly, DO
Paper Chase 2: Antipsychotics + Parkinson’s Disease = Bad CombinationFrom July 2016, Creme de la Thyroid
In this study, use of antipsychotics was associated with a significantly increased mortality risk in patients with Parkinson Disease. •5min 59Andrew Buelt, DO and Joe Weatherly, DO
Introduction: DementiaFrom July 2016, Creme de la Thyroid
Dementia is common, and it is devastating. Contrary to popular belief, it is NOT a normal part of aging. Approx 5.2 million Americans over the age of 65 have dementia and this number increases as the boomer generation ages. After the age of 65, the lifetime risk of developing dementia is around …19min 6Heidi James, MD and Rob Orman, MD
Paper Chase 1: PPI’s and Increased Risk of Dementia, It’s Far-Fetched.From June 2016, C Diff Shows No Mercy!
Discuss findings from the recent study by Gomm, Willy, et al. "Association of Proton Pump Inhibitors With Risk of Dementia: A Pharmacoepidemiological Claims Data Analysis." JAMA neurology (2016).6min 36Andrew Buelt, DO and Joe Weatherly, DO