Paper Chase #5: Increased Water Intake in Recurrent UTIs
From January 2022, Maybe 2022 Will Be Better?Increased water intake is an effective antimicrobial sparing strategy to prevent recurrent cystitis in premenopausal women.
5min 39Tom Robertson, MD and Steve Biederman, MD
Paper Chase #4: Quad Pill vs Monotherapy for HTN
From January 2022, Maybe 2022 Will Be Better?The quad pill achieved better BP control with no difference in adverse effects.
5min 27Tom Robertson, MD and Steve Biederman, MD
Paper Chase #3: Effect of School Interventions on Asthma Symptoms
From January 2022, Maybe 2022 Will Be Better?Neither a pest management program nor a HEPA filter significantly reduced symptom days with asthma.
7min 14Tom Robertson, MD and Steve Biederman, MD
Paper Chase #2: Value of Multiple DEXAs in Women Being Treated for Osteoporosis
From January 2022, Maybe 2022 Will Be Better?Variation in BMD in imaging was significant, and only a small portion of women showed sustained BMD changes on serial imaging.
6min 58Tom Robertson, MD and Steve Biederman, MD
Paper Chase #1: Maintenance & Discontinuation of Antidepressants in Primary Care
From January 2022, Maybe 2022 Will Be Better?Patients who were assigned to stop their medications had a higher risk of relapse of depression.
7min 2Steve Biederman, MD and Tom Robertson, MD
Paper Chase #5: Apple Cider Vinegar and Weight Management
From December 2021, So Long, 2021The addition of apple cider vinegar showed reduction in weight, and improved metabolic parameters, but there are many limitations.
8min 42Tom Robertson, MD and Steve Biederman, MD
Paper Chase #4: Dose Tapering Effects in Patients on Long Term Opioids
From December 2021, So Long, 2021Tapering events were significantly associated with increased risk of overdose and mental health crisis.
6min 24Tom Robertson, MD and Steve Biederman, MD
Paper Chase #3: Predicting NAFLD for Adults
From December 2021, So Long, 2021The scoring system performed decently, although implementation in conjunction with other recommendations is unclear.
7min 20Tom Robertson, MD and Steve Biederman, MD
Paper Chase #2: Salt Substitutes and CV Events, Death
From December 2021, So Long, 2021Among people with history of stroke or more than 60 years old with high blood pressure, rates of stroke, major cardiovascular events, and death were lower with salt substitute than with regular salt.
7min 58Tom Robertson, MD and Steve Biederman, MD
Paper Chase #1: Tubes vs Med Management for Recurrent Otitis Media
From December 2021, So Long, 2021Minimal differences were found between TT and medical treatment.
6min 48Tom Robertson, MD and Steve Biederman, MD
Paper Chase #5: Vitamin C and the Common Cold
From November 2021, Staying SafeVitamin C supplementation significantly reduced the frequency of the common cold but had no apparent effect on duration or severity
7min 54Steve Biederman, MD and Tom Robertson, MD
Paper Chase #4: Frailty and DOACs vs Warfarin in Older Adults with A-Fib
From November 2021, Staying SafeApixaban had the greatest risk reduction in adverse effects in frail patients
6min 1Steve Biederman, MD and Tom Robertson, MD
Paper Chase #3: Decompression Plus/Minus Fusion in Spondylolisthesis
From November 2021, Staying SafeDecompression alone was noninferior to decompression and fusion over a period of two years, but reoperation occurred somewhat more often in the decompression only group
6min 20Steve Biederman, MD and Tom Robertson, MD
Paper Chase #2: Cabotegravir for HIV Prevention
From November 2021, Staying SafeCabotegravir was superior to daily oral medication in preventing HIV infection
5min 18Steve Biederman, MD and Tom Robertson, MD
Paper Chase #1: App-Based Support for Low Back Pain
From November 2021, Staying SafePatients who used the app as an adjunct to usual care had reduced pain-related disability at 3 months, but this improvement was small and of uncertain clinical significance
6min 47Steve Biederman, MD and Tom Robertson, MD
Paper Chase #5: Probiotics to Prevent Antibiotic Associated Diarrhea or C Diff
From October 2021, Reducing HarmProbiotics did not show a statistical difference in the incidence of AAD or CDAD
7min 35Steve Biederman, MD and Tom Robertson, MD
Paper Chase #4: Azithro vs Doxy in Rectal Chlamydia
From October 2021, Reducing HarmA 7-day course of doxycycline was superior to single-dose azithromycin in treatment of rectal chlamydia
5min 6Steve Biederman, MD and Tom Robertson, MD
Paper Chase #3: High-Sensitivity Troponin in Kidney Disease
From October 2021, Reducing HarmHs-trop was more commonly elevated in patients with renal impairment, and these elevations were less frequently attributed to MI.
6min 19Steve Biederman, MD and Tom Robertson, MD
Paper Chase #2: Aspirin Dosing in CV Disease
From October 2021, Reducing HarmThere were no significant differences in cardiovascular events or major bleeding between patients assigned to 81 mg and those assigned to 325 mg
7min 30Steve Biederman, MD and Tom Robertson, MD
Paper Chase #1: The BEYOND Trial for Diabetes
From October 2021, Reducing HarmGlycemic control was similar between all groups, with increased patient satisfaction and less hypoglycemia in the basal-GLP1/SGLT groups
7min 52Steve Biederman, MD and Tom Robertson, MD
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