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Hypogonadism Pt 2: Initiating Treatment, Risks of Therapy, Monitoring Patients

Joe Weatherly, DO and Margaret Wierman, MD
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No me gusta!

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Obese patients with low testosterone may get significant benefit from weight loss.

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Michael S. -

Some questions:
>>> 1) I've heard from more than one urologist that all reference ranges
>>> for testosterone, free and total, are useless.
>>> 2) Testosterone binds not only to SHBG but also to albumin albeit in
>>> a far more irreversible fashion. This means that while testosterone
>>> bound to SHBG and the free version are biologically active,
>>> testosterone bound to albumin is not. This means that free
>>> testosterone undermeasures active hormone while total overmeasures it.
>>> 3) As a result there is an assay called bioavailable testosterone
>>> which measures only free and SHBG-bound hormone. I was wondering about
>>> your opinion on that.
>>> 4) You mentioned injectable and transdermal preparations but there is
>>> an oral version, used to be called Andriol before it went generic.
>>> Works well but has to be taken with fat to be absorbed. I was
>>> wondering why that wasn't mentioned.

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Where Has All The Testosterone Gone? Full episode audio for MD edition 170:03 min - 80 MB - M4AHippo Primary Care RAP March 2016 Summary 696 KB - PDF

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