- Mailbag Extravaganza, Continued!16:16Practical Diabetes Care: How Do I Order That?Free Chapter25:36Paper Chase #1 - Bacterial Contamination on Stethoscopes5:52Polycythemia Vera - Part 121:01Croup15:25Paper Chase #2 - Oral Anticoagulants and PPIs and Upper GI Bleed6:23Polycythemia Vera - Part 210:34OB Potpourri19:07Paper Chase #3 - Vitamin D & Prevention of CA & CV Disease3:49Probiotics10:33Incidental Lung Nodules12:06Paper Chase #4 - Outcomes After Hospitalization with Anemia4:46Wandering in Dementia11:07Clinical Reasoning19:20Paper Chase #5 - CV Outcomes in Previous MI and Mild DM Following Pioglitazone4:28The Summary6:08
Polycythemia vera is a relatively rare myeloproliferative disorder characterized by increased RBC production. In this segment, our own Matt DeClerck interviews Hematology guru Dr. Tom Deloughery on the in’s and out’s of PV. Clinical suspicion for PV should occur in any patient with elevated RBC mass, elevated Hgb/Hct, aquagenic pruritus, erythromelalgia, and/or systemic thrombi (MI, stroke, DVT, etc). Diagnosis is confirmed by presence of the JAK2 gene mutation. Treatment is focused on decreasing RBCs with phlebotomy and/or cytoreductive therapy; symptom control; and treatment/prevention of arterial or venous thrombi.