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Fever in the Patient with HIV

Heidi James, MD
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Fever in HIV-AIDS patients remains a challenge. HAART has contributed to a decrease in its incidence but has not altered the spectrum of causes. It is a common cause of admission to hospitals and is associated with substantial cost and significant mortality. In most cases fever of unknown origin in the context of HIV is a result of occult opportunistic infection and physicians should take into consideration differing geographic prevalences of infectious pathogens. If no infectious cause can be demonstrated, AIDS-related lymphoproliferative diseases and drug fever should be considered along with an number of less common etiologies. The diagnostic work-up is initially directed toward infection, which remains the single leading etiology. The single most important early investigation is blood culture. Bone marrow examination, liver biopsy, and newer nuclear imaging techniques are useful further diagnostic modalities. An algorithm for the diagnostic approach and management of patients with HIV-associated fever of unknown origin is presented.

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A Hyperthyroid Fetus Full episode audio for MD edition 181:09 min - 85 MB - M4AHippo Primary Care RAP June 2018 Written Summary 1 MB - PDF

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