Episode Chapters
- Proctalgia Fugax13:22Knee X-Rays15:42Paper Chase #1 - Oseltamivir vs Usual Care in ILI6:30Peritoneal Dialysis, Part 1Free Chapter19:55Telling Pain Syndromes Apart14:40Paper Chase #2 - Unnecessary Pelvic Exams and Pap Smears7:27Peritoneal Dialysis, Part 218:09Alcohol Use in Pregnancy9:44Paper Chase #3 - Alcohol Abstinence in Drinkers with Atrial Fibrillation5:28Ode to the Node: Pediatric Lymphadenopathy27:10Scribes in Health Care20:34Paper Chase #4 - Effectiveness of Different Treatments for Opioid Use Disorder7:19The Breast Exam21:49Paper Chase #5 - Vit D and Calcium for Fracture Prevention8:24Mailbag12:50
Primary Care RAP Written Summary May 2020 981 KB - PDF
David E. - May 2, 2020 2:26 PM
excellent
Neda F., MD - May 2, 2020 2:28 PM
Thanks, David! -- Neda
Chris - May 24, 2020 7:34 AM
I might have just missed it, but other than the anticholinergic effects we should be considering the potential QT prolonging effects of trazodone. On the hospitalist side of things we're lucky to have a recent ECG on almost everyone and easy access to an ECG if not, but I imagine that even when prescribing for outpatients it would be reasonable to consider getting an ECG if you're going up to higher doses of trazodone or if the patient is concurrently on any other potentially QT prolonging agents even if you're considering just a low dose of trazodone?
Neda F., MD - May 28, 2020 3:19 AM
Hi Chris. That's a great point. From what we researched, the risk of QTc prolongation with the use of trazodone alone is quite low, <1% according to Up to Date and "not associated with clinically significant increases in QTc intervals at therapeutic doses" according to this US Pharmacist resource: https://www.uspharmacist.com/article/qtc-prolongation-with-antidepressants-and-antipsychotics. Certainly if they're on more than one med that might prolong QTc, or if they have other CV risk factors, it would be wise to check an ECG beforehand.