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New A-Fib Guidelines: NOACs Over Warfarin

Tarlan Hedayati, MD, Neda Frayha, MD, and Matthew DeLaney, MD, FACEP, FAAEM
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 It is now recommended that NOACs are chosen over warfarin, in patients with atrial fibrillation, except in patients with moderate to severe mitral valve stenosis or a mechanical heart valve.

 
 

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Ian L., Dr -

Researches are claiming the ability to measure the effects of the NOAC's on factor X for example Kim Paul Y et al. An assay to measure levels of factor Xa inhibitors in blood and plasma - Journal of thrombosis and Haemostasis April 2019 so these tests are in demand for meeting the concerns of overdose adherence and levels when bleeding does occur either spontaneously or with trauma and also if a stroke occurs despite therapy .
Still the claims that apixoban for example has half or even less the intracranial bleeding risk of warfarin with but with equal efficacy in preventing stroke is obligating the provision of reliable assays .

sarah j. -

I believe the new ACC guidelines recommend anticoagulation for men with a CHADS-Vasc Score greater than or equal to 2 and women with a score greater than or equal to 3, right? Podcast quotes greater than 2 and greater than 3 for both sexes, respectively.

Neda F., MD -

Thanks for sharing this, Sarah. - Neda

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Primary Care RAP March 2020 Written Summary 1,010 KB - PDF

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