Episode Chapters
- All About Amitriptyline16:11Paper Chase #1: Antibiotics vs Appendectomy for Appendicitis7:26Proceed With Confidence: Onychocryptosis22:17Paper Chase #2: Memory Training for Children5:08Keeping Up with the Literature with Dr. Alan EhrlichFree Chapter25:58Light Chains, SPEPs, and MGUS23:50Paper Chase #3: Palliative Care and Chronic Illness6:28Primary Care of Gay, Bisexual and Other Men Who Have Sex With Men: Part 119:34Primary Care of Gay, Bisexual and Other Men Who Have Sex With Men: Part 28:04Paper Chase #4: Patient-Reported Errors in EHR Notes6:11Group Prenatal Care18:10Tips for Getting Paid!29:23Paper Chase #5: Smoking Cessation in New Cancer Diagnoses6:36Mailbag: Intuitive Eating14:52
Kappa? Lambda? SPEPs? MGUS? WTH? Hematologist Dr. Victoria Giffi walks us through a clear, helpful primer on this alphabet soup of immunoglobulins.
Hippo Primary Care Written Summary February 2021 480 KB - PDF
Stephen P. - February 5, 2021 1:02 PM
If an elevated alpha or beta globulin is noted on spep as part of ruling out myeloma, is that an abnormality requiring a workup and if so what is one looking for? Thanks for an excellent review getting me closer to understanding a challenging topic!
Neda F., MD - February 17, 2021 3:40 AM
Stephen, we're so glad! Here's Dr. Giffi's response to your question:
"So elevated alpha and beta globulin do not represent a clonal process either. They usually are reflective of inflammation, the cause of which could be many things.
I would think of this workup as similar to that of an elevated ESR or CRP - other nonspecific markers of inflammation. The list includes infections both acute and chronic, autoimmune and malignant."
We hope this helps! Take care -- Neda