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Paper Chase #2 - COMPASS Trial

Steve Biederman, MD and Tom Robertson, MD
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06:22
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To evaluate the efficacy of rivaroxaban alone or in combination with aspirin for secondary prevention of CV disease.

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Gareth O., Dr -

Howdy folks, nice topic.
What do you think about extrapolation to patients with atrial fibrillation and concomitant stable atherosclerotic disease? It sounds like we could get away with noac monotherapy instead of continuing full dose noac plus aspirin as we tend to do. Be interested to hear your thoughts on this.
G

Neda F., MD -

Hi Gareth. What a great question and hot topic for discussion. We'll add this to our list of questions to cover! Thanks so much for listening and writing in. -- Neda

Jenn H., MD -

Sepsis talk: Aren't we getting away from Zosyn + Vanc combo due to elevated risk of AKI? I've been seeing a lot more cefepime + vanc instead. So run cefepime first? I'm guessing this is also more rapid to infuse and more well tolerated?

Neda F., MD -

Hi Jenn. Yes, I agree, and so do our Paper Chase duo! I've asked Dr. Shah to weigh in with any additional thoughts he has, and I'll keep you posted. -- Neda

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A World of (Bladder) Hurt Full episode audio for MD edition 186:36 min - 88 MB - M4AHippo Primary Care RAP - March 2019 Written Summary 1 MB - PDF

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0.25 Free AMA PRA Category 1 Credits™ certified by Hippo Education or 0.25 Free prescribed credits by the American Academy of Family Physicians certified by AAFP (2019)

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