ERcast: Clinical Perspectives Podcast Preview

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Essentials Masterclass: Trauma Articles You Gotta Know

Chris Hicks, MD, Andy Little, DO, and Drew Kalnow, DO

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The summary below is from an episode of ERcast: Clinical Perspectives

Hemorrhagic trauma kills through coagulopathy, occult shock, and missed vascular injury before classic hypotension declares itself. Early calcium replacement during massive transfusion, narrow pulse pressure as a pre-crash warning sign, and broader CT angiography use for blunt cerebrovascular injury all have practice-changing implications in trauma resuscitation.

Practice-Changing Trauma Resuscitation Pearls

  • Early calcium replacement: Hypocalcemia is common from hemorrhagic shock and citrate load during transfusion, and ionized calcium below 1 mmol/L tracks with higher mortality, greater blood use, and worse coagulopathy.
  • Massive transfusion calcium strategy: Calcium gluconate should be started early when massive transfusion begins rather than waiting for the labs to drift, with a practical ED dosing cadence we lay out in the episode.
  • Narrow pulse pressure warning: A pulse pressure under 30 mmHg can signal acute blood loss before hypotension appears, because systolic pressure falls while diastolic pressure is temporarily preserved by catecholamine surge.
  • Prehospital crash predictor: Normotensive trauma patients with narrow pulse pressure still carry higher mortality and greater need for emergent intervention, making this an early cue to have blood products ready.
  • BCVI stroke prevention: Blunt cerebrovascular injury includes carotid or vertebral dissection and pseudoaneurysm, and missed lesions can progress to thromboembolism and stroke despite an initially distracting trauma presentation.
  • CTA screening expansion: Denver criteria miss a meaningful share of clinically important BCVI, especially higher-grade injuries, so CTA deserves a lower threshold in major blunt trauma. We get into the imaging trigger points in the chapter.

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References:

  1. Vasudeva M, et al. Hypocalcemia in trauma patients: A systematic review. J Trauma 2020, 90(2) 396-402. PMID: 33196630. 
  2. Schellenberg M, et al. Prehospital Narrow Pulse Pressure Predicts need for Resuscitative Thoracotomy and Emergent Intervention after Trauma. J Surg Research 2021, 268: 284-290. PMID: 34392182.
  3. Leichtle SW, et al. Blunt cerebrovascular injury: The case for universal screening. J Trauma 2020, 89(5): 880-886. PMID: 32520898.

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