ERcast: Clinical Perspectives Podcast Preview

Hippo ERcast May 2025

  • May 2025
  • 9 Chapters
  • 2 hr 37 min

Welcome to the May 2025 Edition of ERcast! We are starting the month with DeLaney, Andy, and Drew, who discuss what it takes to make Emergency Medicine a long-term career. Dr. Tiffany Proffitt joins us to review the most common ENT complaints and to give us tips on management for these patients. EM physician, Steven Haywood, joins us to discuss how to rock your next procedural sedation. Brit Long guides us through key tips that we need to make this crucial diagnosis at the bedside. OBGYN Megan Jones returns to answer your burning OB questions. Andy and Drew bring us all the details for the Grace 4 Updates in Alcohol Withdrawal. Finally, Cam and Drew give us 3 articles to review in Lit Matters. Enjoy!

 

Faculty

  • Andy Little, DO

    Dr. Andy Little is an emergency medicine physician and educator. He earned his medical degree from the Ohio University Heritage College of Osteopathic Medicine and completed his emergency medicine residency at OhioHealth Doctors Hospital Emergency Medicine Residency, where he served as Chief Resident. He has received multiple national awards, including recognition from the American Osteopathic Association, American College of Osteopathic Emergency Physicians, and Emergency Medicine Residents' Association.

  • Cameron Berg, MD

    Based in Minneapolis, MN, Dr. Berg focuses on simplifying complex patient care processes, such as chest pain, syncope, and heart failure treatment. Since 2020, he has also been navigating his own recovery from a TBI after a bicycle accident. When he isn't in the clinic, Cameron is usually busy keeping his three young children alive and happy.

  • Matthew DeLaney, MD, FACEP, FAAEM

    Dr. Matthew DeLaney is an emergency medicine physician and educator based in Birmingham, Alabama. A native of Mobile, he earned his medical degree from the University of South Alabama and completed his emergency medicine residency at Maine Medical Center.Dr. DeLaney has experience in both community and academic emergency medicine and is known for his commitment to teaching and medical education. He lives in Birmingham with his wife, Erin, who is also a physician, and their two daughters.

  • Brit Long, MD

    Dr. Brit Long is a Professor of Emergency Medicine at the University of Virginia and an emergency medicine physician with experience in both a community ED and at a military academic center ED. He is the Clinical Editor-in-Chief of emDOCs.His professional interests include medical education, evidence-based medicine, and the FOAMed movement. Outside of work, he enjoys spending time with his wife and two daughters

  • Drew Kalnow, DO

    Dr. Drew Kalnow is an emergency medicine physician and educator based in Columbus, Ohio. He completed his emergency medicine training at OhioHealth Doctors Hospital Emergency Medicine Residency. Dr. Kalnow is passionate about advancing emergency medicine through high-quality education, with a particular focus on simulation, learning theory, and innovative teaching.

  • Tiffany Proffitt, DO

    Dr. Proffitt is a board-certified Emergency Medicine physician practicing in Scottsdale, Arizona. She completed her medical training at Midwestern University Chicago College of Osteopathic Medicine and found her passion for medical education during her residency at Spectrum Health Lakeland. Tiffany is the co-founder and co-chairwoman of the HonorHealth Women Physicians Leadership Council, where she works to enhance professional development for 550 women clinicians. When she isn’t in the ED or podcasting, she’s chasing twins, dancing with toddlers, and enthusiastically singing the wrong lyrics to every song.

  • Megan Jones, MD
  • Steven Haywood, MD

Chapters

Career Longevity

Emergency medicine can be a sustainable long-term career, but only if workload, finances, and recovery are managed deliberately. Burnout risk rises when early-career physicians chase debt payoff or lifestyle inflation with extra shifts, while durable careers tend to come from a pace that matches real life outside the ED. Sustaining a Long EM Career Sustainable pace early: Early-career overworking is a common setup for burnout, especially when extra shifts are used to crush debt fast instead of building a schedule you can realistically maintain for years. Lifestyle inflation trap: Career longevity often depends less on maximizing income than on avoiding an ever-expanding standard of living that quietly turns optional shifts into financial necessity. Work life calibration: A durable emergency medicine career usually requires explicit tradeoffs around vacation, family time, and financial goals rather than assuming more work now will feel harmless later. We get into those tradeoffs in the episode. The centurion model: Some physicians thrive in the ED for decades, and that longevity appears tied to unusual resilience and tolerance for shift-work stress rather than a universal formula. No mandatory off ramp: Not every emergency physician needs to reduce shifts or plan an exit strategy, but long careers are more plausible when pacing is intentional and personal limits are respected.

Non-Bleeding ENT

ENT foreign bodies and dental trauma hinge on time-sensitive tissue protection, not just extraction. Ear and nasal button batteries can cause rapid necrosis, while permanent tooth avulsion success falls quickly with extra-alveolar time and proper handling. Ear and Nasal Foreign Bodies Positioning and visualization: Successful ear foreign body removal starts with lateral recumbent positioning or upright alignment, a strong light source, and every tool laid out before you touch the canal. Insect immobilization first: Live bugs should be drowned with mineral oil or viscous lidocaine for about 15 to 20 minutes before removal, which turns a chaotic extraction into a controlled one. Organic material caution: Rice, bread, corn, and other organic matter should not be irrigated because they swell in the canal; forceps or suction are the safer first-line tools. Cerumen rescue option: When hydrogen peroxide is not enough for cerumen impaction, liquid docusate is a useful softening alternative with a mechanism most emergency clinicians will recognize. Post-extraction canal care: After removal, inspect for canal abrasions or lacerations and treat traumatic otitis externa risk with ofloxacin 0.3% otic drops, 10 drops daily for 7 days. Button battery urgency: Ear and nasal button batteries are true time-critical ENT emergencies because soft-tissue injury can begin within hours; the removal threshold and ENT escalation are worth hearing in the episode. Dental Trauma Pearls Primary tooth priorities: In children with injured primary teeth, the main job is screening for associated facial trauma and aspiration rather than heroic salvage, since the tooth is destined to exfoliate. Permanent avulsion handling: Handle an avulsed permanent tooth by the crown, rinse it briefly for 10 seconds, and keep it in milk or reimplant promptly; ideal survival is roughly 15 to 30 minutes. Missing tooth red flag: If an avulsed tooth is not accounted for, treat aspiration as a real possibility and get a chest x-ray rather than assuming it was swallowed or lost at the scene. Luxation and extrusion stabilization: Partially displaced permanent teeth can often be gently repositioned and flexibly splinted to a neighboring tooth, with a practical glue-drying trick we share in the chapter. Ellis fracture framing: Ellis class tracks depth of injury: enamel alone is class 1, while dentin or pulp exposure in class 2 or 3 needs sealing, often with calcium hydroxide paste, plus urgent dental follow-up. Aftercare basics: Dental trauma disposition centers on a soft diet, avoiding contact sports, a soft toothbrush, and chlorhexidine 0.1% mouth rinse twice daily for one week.

Lit Matters #1: Unfractionated Heparin for PE - effective or antiquated?

Unfractionated heparin produces highly variable anticoagulation in acute pulmonary embolism, with aPTT frequently remaining subtherapeutic through the first 48 hours. For most PE patients, the traditional appeal of heparin as a readily reversible bridge looks weaker when advanced procedures are uncommon. Unfractionated Heparin in Acute PE Variable early anticoagulation: Standard unfractionated heparin dosing for acute PE delivered inconsistent aPTT control, with no 6-hour checkpoint showing even half of patients in the therapeutic range. Six-hour aPTT reality: At 6 hours, only 13.9% of bolus-plus-infusion patients were therapeutic, while 51.3% remained subtherapeutic and 34.8% were already supratherapeutic. Forty-eight-hour underdosing: By 48 hours, just 28.4% of bolus-plus-infusion patients were therapeutic and 60.6% were still subtherapeutic, arguing against reliable early PE treatment with UFH. Therapeutic control over time: Not until 36 hours did half of patients achieve even a single therapeutic aPTT, a useful reality check when heparin is assumed to provide prompt dependable anticoagulation. Procedural justification questioned: The usual argument for UFH in PE is easy interruption before thrombolysis or embolectomy, but advanced interventions were rare in this cohort. We get into why that matters in the episode.

High Risk, Low Prevalence: Mesenteric Ischemia

Mesenteric ischemia is a deadly abdominal pain diagnosis with highly variable presentations and mortality that rises with delayed recognition. The key emergency medicine move is to think beyond the classic “pain out of proportion” story, get CTA-based imaging early, and start resuscitation while surgery is mobilized. Recognizing Mesenteric Ischemia Early Four mechanism framework: Mesenteric ischemia comes in four distinct forms—arterial embolism, arterial thrombosis, venous thrombosis, and non-occlusive disease—and the history changes meaningfully with each subtype. Classic presentation limits: Sudden severe pain out of proportion to exam fits embolic SMA ischemia, but more than a quarter of those patients still do not read like the textbook. We get into the bedside pattern recognition in the episode. Thrombotic pain pattern: Arterial thrombosis behaves like an ACS of the gut, with postprandial cramping, food fear, and weight loss after often extensive prior negative workups. Low flow red flags: Non-occlusive ischemia should move up the list in shock states such as sepsis, cardiogenic shock, or hemodialysis, where hypotension drives bowel hypoperfusion. Venous thrombosis clues: Mesenteric venous thrombosis is essentially a massive DVT of the gut, often affecting younger patients with cancer, recent surgery, prior VTE, or other hypercoagulable states. Diagnosis and ED Management CTA over routine CT: Triphasic multidetector CT angiography is the test of choice, with sensitivity and specificity above 95%; a standard contrast CT with venous phase alone cannot exclude the diagnosis. Venous phase necessity: If triphasic imaging is unavailable, a CT angiogram plus an added venous phase is the practical alternative, and it should not wait on lab results. Labs cannot rule out: Lactate may be normal early because hepatic clearance can mask evolving ischemia, and D-dimer is too nonspecific to rescue the diagnosis when suspicion is real. Early ED treatment: Initial management is fluids, broad-spectrum antibiotics, and unfractionated heparin, treating bowel ischemia like a time-sensitive vascular emergency rather than an undifferentiated belly pain. Vasopressor caution: Avoid vasopressors when possible because intestinal vasospasm can worsen ischemia; the disposition hinge is early surgical consultation and rapid revascularization planning.

Calming the Chaos: ED Procedural Sedation

Procedural sedation in the emergency department is safest when it starts with patient selection, monitoring, and choosing the right drug for the procedure. Waveform end-tidal CO2 is a key early warning tool, and many common sedatives provide no analgesia at all. Procedural Sedation Core Principles Early sedation commitment: Procedural sedation often improves workflow and patient experience when painful reductions or repairs are recognized early, rather than after a prolonged, traumatic attempt without adequate control. Waveform capnography priority: Waveform end-tidal CO2 is the most important monitoring adjunct because it detects hypoventilation before pulse oximetry lags, a distinction worth hearing in the episode. Essential team setup: Safe sedation starts with continuous SpO2, ECG, frequent blood pressure checks, IV access, oxygen, suction-ready airway equipment, and enough staff to separate airway watch from the procedure. Analgesia versus anxiolysis: Propofol, midazolam, and etomidate do not treat pain, so matching the agent to the procedure matters as much as achieving sedation depth. ASA risk boundary: ASA class 3 or higher should trigger caution because comorbidity increases sedation risk and may push the case toward anesthesia support or a more controlled setting. Medication Selection and Practical Decisions Ketamine sweet spot: Ketamine is a strong choice for short painful procedures because it provides both dissociation and analgesia while generally preserving airway reflexes and hemodynamics. Propofol reduction use: Propofol is useful when deeper sedation and muscle relaxation help a reduction succeed, but hypotension and respiratory depression remain its headline liabilities. Etomidate limitation: Etomidate is fast on and fast off, but fasciculations and muscle tightening make it a weaker fit for many orthopedic reductions. NPO timing reality: Recent oral intake is a consideration, but aspiration risk correlates poorly with strict NPO times in many emergency scenarios. We get into the real-world tradeoffs in the chapter. Solo sedation pragmatism: Solo procedural sedation may still be reasonable in rural or understaffed settings if nursing and respiratory support are strong and vigilance is uncompromising. Alternatives before sedation: Regional anesthesia and non-opioid analgesia should be considered before sedation when they can control procedural pain with less physiologic risk.

Lit Matters #2: Anticoagulation Trends in PE

Unfractionated heparin remains the dominant initial anticoagulant for acute pulmonary embolism in US hospitals despite guideline support for LMWH and the practical advantages of DOACs. Across 2011 to 2020, UFH use rose while LMWH fell and DOAC adoption climbed from essentially none to a meaningful minority. PE Anticoagulation Practice Trends UFH remains dominant: Initial treatment with unfractionated heparin increased from 41.9% to 56.3% over the decade, making the least predictable option the most common real-world starting choice for acute PE. LMWH use declined: Low molecular weight heparin fell from 58.1% to 37.3% even though it offers more stable pharmacokinetics, avoids serial aPTT or anti-Xa titration, and carries less HIT risk than UFH. DOAC adoption increased: Direct oral anticoagulants rose from 0% in 2011 to 6.4% in 2020, tracking with FDA approvals and later guideline uptake. We get into why the curve still stayed surprisingly shallow in the episode. Therapeutic heparin problem: Only about 22% to 25% of patients on UFH reach therapeutic levels in prior PE studies, a persistent pharmacology gap that helps explain why many clinicians question UFH as a default. Outcomes stayed modest: Median hospital stay fell from 4 days to 3 days, while in-hospital mortality held near 2.4%, suggesting major shifts in initial anticoagulant choice did not obviously move these top-line inpatient outcomes. Who Still Gets UFH ICU-level illness signal: ICU admission was the strongest predictor of UFH use, with an adjusted odds ratio of 6.90, reinforcing that clinicians still favor a quickly reversible agent when PE looks sick or unstable. Escalation therapy association: Systemic thrombolysis and early vasopressor use were both linked to UFH selection, consistent with a high-risk PE mindset where procedural flexibility often drives the first anticoagulant choice. Renal dysfunction effect: Chronic kidney disease and acute renal failure on admission both pushed clinicians toward UFH, a familiar pattern whenever drug clearance and reversibility start to dominate bedside decisions. Hospital-type variation: Large teaching hospitals and Northeastern centers were more likely to start UFH, while smaller and rural hospitals leaned away from it, showing that PE anticoagulation remains highly practice-pattern dependent. Reversibility misnomer: The idea that LMWH blocks later thrombolysis or catheter-based escalation is overstated, and that practical distinction is worth hearing in the episode.

Burning Questions Around Pregnancy With an OB

Early-pregnancy bleeding demands a structured ED approach: ultrasound on every symptomatic visit, selective pelvic exam based on bleeding severity, and Rh immunoglobulin planning by gestational age. Ectopic pregnancy, placenta previa, and miscarriage counseling each carry management and documentation traps that matter in real time. Early Pregnancy Bleeding Evaluation Ultrasound every symptomatic visit: Patients under 20 weeks with concerning bleeding or pain need ultrasound at each ED visit to distinguish threatened from missed abortion, confirm cardiac activity, and assess subchorionic hemorrhage. POCUS as acceptable bridge: A formal study is preferred for dating and anatomy, but ED bedside ultrasound is sufficient when formal imaging is not readily available, a practical distinction we get into in the episode. Pelvic exam timing: Heavy acute bleeding calls for pelvic exam before ultrasound to look for an open cervix or fetal tissue, while stable patients with minimal bleeding can reasonably go to ultrasound first. RhIg by gestational age: Society for Maternal-Fetal Medicine guidance supports RhIg for all Rh-negative pregnant patients, with ED administration emphasized after 12 weeks and clinic follow-up acceptable before that. Previa, Ectopic, and Medication Decisions Transient early placenta previa: Placenta previa is commonly seen from 12 to 20 weeks because the placenta is fully grown before the uterus enlarges, and many apparent previas resolve by 20 weeks. Speculum exam with previa: Known previa is not an automatic no-touch diagnosis in early pregnancy; a gentle speculum exam can still assess the cervix, with later bleeding cases generally needing labor and delivery evaluation. Methotrexate candidate profile: Methotrexate is reserved for suspected unruptured ectopic pregnancy in a hemodynamically stable patient who can comply with close follow-up and has no major hepatic, renal, or hematologic contraindication. Documentation for legal protection: When methotrexate is given from the ED, document nonviability and the direct maternal threat from ectopic pregnancy clearly, and know your state's abortion laws. We lay out the charting nuance in the chapter. Miscarriage Counseling and Follow-up Normalize the prevalence: Miscarriage affects up to 30% of pregnancies, and roughly 70% of first-trimester losses are tied to genetic causes rather than anything the patient did. Future fertility reassurance: One miscarriage usually does not predict infertility; about 85% of women will go on to have a healthy normal pregnancy after a single loss. Immediate emotional language: Start with condolences and explicitly say the loss was not the patient's fault, a small bedside move that often matters as much as the medical plan. Follow-up urgency by outcome: Retained products and missed abortion need immediate OB follow-up, while a completed abortion in a stable patient can usually be seen within a week; we cover the practical disposition distinctions on the show. Trying again timeline: There is no fixed medical waiting period before attempting conception again after miscarriage; patients can resume when they feel emotionally ready and have appropriate follow-up.

Grace-4 Guidelines: Alcohol and Cannabinoids

Alcohol withdrawal is not just a benzodiazepine problem; admitted patients with moderate to severe withdrawal appear to do better when phenobarbital is added. Separately, emergency care for alcohol use disorder now includes anti-craving medications, and cannabinoid hyperemesis syndrome responds better to dopamine antagonists than to typical antiemetics alone. Alcohol Withdrawal and Alcohol Use Disorder Phenobarbital adjunct therapy: For admitted adults with moderate to severe alcohol withdrawal, adding phenobarbital to benzodiazepines is associated with less intubation, fewer ICU admissions, and shorter hospital stay. Delirium and restraint reduction: The signal with phenobarbital is broader than symptom control alone, with lower rates of delirium, less continuous-infusion sedation, and less need for physical restraints. Follow-up after withdrawal care: Alcohol withdrawal treatment should not end at discharge; patients treated in the ED should be offered follow-up addiction care whenever that pathway exists, and we get into the practical handoff in the episode. Naltrexone first-line option: For patients with alcohol use disorder who want to stop drinking, naltrexone is a recommended anti-craving option that can reduce heavy drinking and can be started as an ED bridge when opioids are not on board. Alternatives to naltrexone: Acamprosate is a useful alternative when naltrexone is contraindicated, especially when opioid exposure rules naltrexone out or hepatic issues push you toward another agent. Gabapentin selected use: Gabapentin can reduce heavy drinking days and may help patients with prominent self-reported withdrawal symptoms, but misuse risk and opioid co-use matter when choosing it. Cannabinoid Hyperemesis Syndrome Treatment Dopamine antagonist preference: Cannabinoid hyperemesis syndrome often responds poorly to ondansetron, metoclopramide, or promethazine; haloperidol or droperidol may be more effective for symptom control. Capsaicin as low-risk adjunct: Topical capsaicin has weak efficacy data but a very low risk profile, making it a reasonable adjunct for CHS when usual antiemetics are not getting traction. Usual care still matters: Haloperidol or droperidol are used in addition to usual care rather than instead of it, and the bedside sequencing nuances are worth hearing in the chapter. Outpatient symptom bridge: Olanzapine is a consideration for short-term outpatient symptom relief in selected CHS patients when there is no contraindication, with a few caveats we cover on the show.

Lit Matters #3: Which anticoagulant do providers choose and why?

Acute pulmonary embolism treatment is still shaped as much by habit as by evidence. For most hospitalized PE patients, guidelines favor LMWH or a DOAC over unfractionated heparin, yet clinicians often default to UFH because of perceived reversibility, procedural flexibility, and local culture. Initial Anticoagulation Choice in PE Guideline-concordant first choice: Chest and European PE guidelines favor LMWH and DOACs for initial anticoagulation in most hospitalized patients, not routine UFH-first practice. Therapeutic momentum effect: Initial ED anticoagulation often persists across admission because teams are reluctant to switch agents once treatment is started, a handoff dynamic we get into in the episode. Quick on off belief: UFH was commonly chosen for its supposed quick on/off profile, but that pharmacology rationale was frequently based on clinician misperception rather than meaningful outcome advantage. Procedural flexibility assumption: Many clinicians picked UFH to preserve options for thrombolysis or catheter therapy, even though interviewed interventionalists did not view LMWH as a contraindication to those procedures. Institutional culture inertia: Providers were often agnostic about agent choice and instead followed residency habits, local norms, and unwritten service expectations more than formal PE anticoagulation pathways. Resource burden tradeoff: LMWH-leaning clinicians highlighted that UFH is labor intensive, with infusion management and repeated aPTT checks shifting workload to nurses and patients without clear added benefit.