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Spontaneous Carotid Dissection

Rob Orman, MD and Alan Sielaff, MD

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The summary below is from an episode of ERcast: Clinical Perspectives

Spontaneous carotid and vertebral artery dissection can present as isolated facial pain, headache, or neck pain with a completely normal neurologic exam. In younger patients, cervical artery dissection accounts for up to 25% of strokes, and the miss often starts with false reassurance from reproducible tenderness or a familiar migraine story.

Spontaneous Cervical Artery Dissection

  • Normal exam false reassurance: Cervical artery dissection may look benign at first: normal vitals, normal neuro exam, and even focal TMJ or trapezius tenderness do not exclude a dangerous carotid or vertebral lesion.
  • Pain-only presentation pattern: Unilateral headache, facial pain, or neck pain are common presenting symptoms, and embolic complications may be delayed rather than obvious on the first ED visit.
  • High-yield associated clues: Partial Horner syndrome, pulsatile tinnitus, cranial or cervical neuropathy, and posterior-circulation findings like Wallenberg syndrome should sharply raise suspicion.
  • Younger stroke epidemiology: Up to 25% of strokes in younger patients are linked to cervical artery dissection, with higher prevalence in connective-tissue disease, pregnancy or postpartum state, smoking, and even minor neck torque. We get into the easy-to-overlook triggers in the episode.
  • Imaging test selection: CTA and MRA are both used for diagnosis; some radiologists favor CTA for vertebral artery evaluation, while carotid imaging is often reasonable with either modality.
  • Initial antithrombotic approach: Aspirin is standard treatment for most uncomplicated cases, while dual antiplatelet therapy adds bleeding risk without clear routine benefit in the usual presentation.

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References:

  1. Robertson JJ, Koyfman A. Extracranial Cervical Artery Dissections. Emerg Med Clin North Am. 2017 Nov;35(4):727-741. PMID: 28987426.
  2. Caplan, A., and A. Sharma. "Stop Yelling: A Rare Cause of Internal Carotid Artery Dissection (ICAD) in a Young Professional." Ann Stroke Vasc Neurol 1.1 (2020): 1002.
  3. Hakimi, Ryan, and Sanjeev Sivakumar. "Imaging of carotid dissection." Current pain and headache reports 23.1 (2019): 2.
  4. Popp, Daniel, et al. "Modified Split-Scan Computed Tomography (CT) Diagnostics of Severely Injured Patients: First Results from a Level I Trauma Center Using a Dedicated Head-and-Neck CT-Angiogram for the Detection of Cervical Artery Dissections." Journal of Clinical Medicine 9.8 (2020): 2568.
  5. Nebelsieck J, Sengelhoff C, Nassenstein I, et al. Sensitivity of neurovascular ultrasound for the detection of spontaneous cervical artery dissection. J Clin Neurosci. 2009;16(1):79-82. doi:10.1016/j.jocn.2008.04.005
  6. Benninger, D. H., and Ralf W. Baumgartner. "Ultrasound diagnosis of cervical artery dissection." Handbook on Neurovascular Ultrasound 21 (2006): 70-84.
  7. Dittrich, R., et al. "Negative ultrasound findings in patients with cervical artery dissection." Journal of neurology 253.4 (2006): 424-433.

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