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Lit Matters 2: Viral Panels on Kids-- Do we Need Them?

Drew Kalnow, DO and Cameron Berg, MD

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The summary below is from an episode of ERcast: Clinical Perspectives

Most children with viral upper respiratory infections improve with supportive care, and broad respiratory viral panels rarely change ED management. In a pediatric emergency department study, comprehensive viral testing increased charges and length of stay without reducing antibiotic use.

Pediatric Viral Panels in the ED

  • Common URI baseline: Children can have up to eight upper respiratory infections per year, making viral URI one of the highest-volume pediatric ED complaints and a setting where low-value testing adds up quickly.
  • Limited management impact: Comprehensive respiratory viral panel results did not improve clinical outcomes for discharged children, reinforcing that history and physical exam usually answer the key bedside questions.
  • Higher patient charges: Respiratory viral panel testing was associated with markedly higher total charges, roughly doubling cost compared with no testing, without a compensating clinical benefit.
  • Longer emergency stay: Testing was linked to a longer ED visit, with length of stay stretching from about 2 hours to 4 hours when a panel was sent. We get into the operational implications in the episode.
  • Antibiotic decision caution: A positive viral test does not rule out a bacterial infection, and panel use was not associated with a meaningful change in antimicrobial prescribing.

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